They grow and develop based off of the collective sum of human thought, while being stated by Cultivation herself to almost entirely exist inside of that dynamic.
I see them as almost exactly the same thing.
I don't consider being an unoathed to be a qualifier for moral consideration.
Even things like sticks, rocks, and ships can make decisions in the Cosmere, I don't think that entitles them to moral value.
Everything in the Cosmere has some level of investiture. Scadrians are actually pretty low on that list. Rosharans, Nalthians, and Threnodites all come in above them in investiture.