I think that can happen, but it would take tremendously long time. Like you were the shard Amity for example, you wouldn't become Abhorrence over night, what is plausible to happen is that the shard would change Vessels A LOT, and each Vessel's Intent must be close to Amity, but not Amity, perhaps closer to Love for example, the next one is Liking, Neutrality Disliking, Hatred, and then finally Abhorrence. And each time the Shard will became a little less stable, till it's as unstable as Harmony. That's my opinion.