It makes sense that Harmonium should create a Feruchemist because Harmonium comes from both Preservation and Ruin. Furthermore, Sanderson has said that you can use God Metals to create a Feruchemist.
However, this has some problems. The first problem is that Harmonium probably didn't exist thousands of years ago at the start of Feruchemy. But, since Harmonium can be forced to split into Lerasium and Atium even when Ruin and Preservation are combined, maybe they could have been forced to combine in a similar way when Preservation and Ruin were separate? The second problem is that simply eating Harmonium obviously doesn't work. Someone would have tried that during the extensive experimentation happening with it on Scadrial. You would need to do something a little more complicated.
Still, I think it is very possible and maybe the most likely option that Harmonium somehow creates Feruchemists!
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