Shades and Investiture

[Jondesu he/him]

Yes, I think so. Remember, (most) investiture comes from shards, and since Mistborn spoilers

Vin took down ruin

we know that shards can take each other down.

That was a bit of an unusual situation, to be fair.  Not saying it's not possible elsewhere, but it doesn't go well for the Shardholder doing the attacking either.  We're not sure exactly what would have happened after that either, had the events in that story not transpired as they did.

 

jW