Starting to think the Roshar vs. Scadrial conflicts we may see in the future will have nothing to do with Retribution, but will instead be perpetuated by Cultivation. Her Shardic intent to me would be acting actively agains both the intents of Ruin and Preservation. I think the "big bad" of the overaching Cosmere storyline will be either Cultivation or Cultivation merged with Retribution, acting to try and destroy Harmony and his agents.
Curios to hear what other peoples thoughts/feelings are on this.
