I woke up at 3am with this question.
Both are currently on Roshar. Nightblood is essentially a Spren with a Command and a ton of investiture. It's limitations are an inability to understand it's Command (what is evil?) or internalise changes (it's creator is dead, etc).
Sja-Anat exists to "enlighten" spren into more than they were. Sja-Anat appears to want to be free of Odium's influence, and nightblood has been able to kill a Vessel.
Do we think there's any potential here?