So this doesn't necessarily have to be done in cartoon form, but I think it's fun this way, and really a good drawing is one that conveys what you are trying to communicate, so go for it sharders, create your cartoon punchline riddles, we're all friends here.
To start things off, here's a rather classy one, where, if you so choose, you can try to figure out what the champagne cork attendant is telling the bottle of wine. If you guess it correctly you will win one genuine upvote, if no one guesses it by tomorrow at this same time (1:20 PST), I'll post the solution:
The cork says to the bottle...